How does Marin^® work?

Marin provides support for the liver with silybin and vitamin E. Marin also contains zinc for additional benefit.

The chart below illustrates that the silybin in Marin which is in a phosphatidylcholine complex has increased bioavailability in dogs, reaching levels up to 4 times more than that seen with 80% standardized milk thistle extracts (silymarin).

Plasma levels of silybin in dogs after oral administration of SPC* versus oral administration of silymarin
Each is given as one oral dose equivalent to 16 mg/kg body weight of silybin.

Filburn CR, Kettenacker R, Griffin D. Safety and bioavailability in beagles of zinc and vitamin E combined with silybin and phosphatidylcholine. Inten J Appl Res Med 2006;4(4):326-334.

*Silybin-phosphatidylcholine complex

Marin is available in a convenient chewable formulation which provides another option for those pets requiring on-going liver support.

Marin, Denosyl, and Denamarin support the liver through differing actions and may be used individually or in combination depending on your pet’s needs. Your veterinarian can advise you on the best way to support your pet's liver.