Released: 7/8/2009

Avocado/Soybean Unsaponifiables (ASU) and Epigallocatechin Gallate (EGCG) Shown Effective at Protecting Cartilage


Edgewood, MD: Nutramax Laboratories, Inc. is pleased to announce results of exciting research recently presented at the 8th World Congress of the International Cartilage Repair Society. The results showed that the combination of avocado/soybean unsaponifiables (ASU) and epigallocatechin gallate (EGCG) is effective at decreasing expression of cyclooxygenase-2 and production of prostaglandin E2 (PGE2) in chondrocytes. Cyclooxygenase-2 regulates the production of PGE2; both are mediators involved in the process of cartilage breakdown. This in vitro study, which used NMX1000® avocado/soybean unsaponifiables, adds to earlier research demonstrating benefits of ASU to joint health and shows that EGCG, a major component of green tea catechins, may potentiate ASU’s effects.

"We are delighted by these results," said Carmelita G. Frondoza, PhD, director of research and development. "They provide corroboration to both veterinarians and pet owners that the use of ASU and EGCG may be a useful modality in the management of joint health."

The combination of NMX1000® avocado/soybean unsaponifiables and EGCG is found in the joint health supplements Dasuquin® for Dogs and Dasuquin for Cats. For more information, please call Nutramax Laboratories, Inc. at (888) 886-6442 or visit www.nutramaxlabs.com.

About Nutramax Laboratories, Inc.:
Products include Cosequin®, the #1 veterinarian-recommended joint health supplement brand; Dasuquin®, the next generation in joint health support; Denosyl®, Marin®, and the combination product Denamarin® for hepatic support; Proviable® multi-strain probiotics; Oxstrin® Optimized for support of antioxidant and nutritional status; Welactin®, to help skin and coat health plus overall wellness; Consil®/Consil Putty synthetic bone graft; and CoMal® Q10. Ask us about new Denamarin and Denosyl chewable tablets for dogs. For more information, visit www.nutramaxlabs.com or call (888) 886-6442.



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