Animal Health Product FAQs

Frequently Asked Questions

On this page you will find frequently asked questions for our animal health products. Use the links below to jump to the product you want to learn more about.

Dasuquin^® for Dogs

Dasuquin^® for Cats

Cosequin^® for Dogs

Cosequin^® for Cats

Cosequin^® Equine Products

Denosyl^®

Denamarin^®

Marin^®

Proviable^® for Dogs and Cats

Proviable^® for Rabbits

Welactin^® for Dogs and Cats

Dasuquin^® for Dogs

Dasuquin^® Dog QuestionsBack to Top

What is Dasuquin for Dogs?

What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?

What is ASU, and how does it work?

How do I know if my dog needs Dasuquin?

My dog has been taking a joint health supplement product. How is Dasuquin different?

My dog’s food contains glucosamine and chondroitin sulfate. Do I still need Dasuquin?

What should I look for when giving Dasuquin?

What else can I do for my dog?

Are there any safety concerns with Dasuquin?

What strengths and sizes is Dasuquin available in?

Where do I purchase Dasuquin?

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

What is Dasuquin^® for Dogs?

Dasuquin from Nutramax Laboratories, Inc. is a joint health supplement for dogs that goes beyond standard glucosamine supplements. It contains NMX1000^®* avocado/soybean unsaponifiables (ASU), decaffeinated tea, FCHG49^®* glucosamine hydrochloride, and TRH122^®* low molecular weight chondroitin sulfate in a tasty chewable tablet. It is the most complete joint support supplement available.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?

The combination of the trademarked FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate supports cartilage production and helps block enzymes in joints that break down cartilage. These ingredients together have been shown in published studies to protect joint cartilage better than either ingredient alone. A greater than additive effect, known as a “synergistic” effect, on cartilage cells was seen using this glucosamine and low molecular weight chondroitin sulfate together.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

What is ASU, and how does it work?

ASU stands for avocado/soybean unsaponifiables, an ingredient concentrated directly from avocados and soybeans that is used for joint health. ASU has been shown to improve joint function and comfort levels. Studies using cartilage cells have shown that ASU lowers the expression or production of several compounds involved in the process of cartilage breakdown in joints. ASU complements the positive effects of the other active ingredients in Dasuquin. The glucosamine in Dasuquin is synergistic with low molecular weight chondroitin sulfate and has been shown in cartilage cell studies to be synergistic with ASU. Of note NMX1000^® avocado/ soybean unsaponifiables, FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate together were shown in cell studies to be better than the combination of glucosamine and chondroitin sulfate alone at inhibiting expression of several agents involved in the breakdown of cartilage. The highly absorbable tea is rich in antioxidants, which have a positive effect on cartilage as well as on overall body defenses.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

How do I know if my dog needs Dasuquin?

It may be a good time to ask your veterinarian about Dasuquin if you notice that your dog slows down during walks, does not get up easily, or is reluctant to climb stairs or jump into the car. Your veterinarian will examine your dog to determine if he/she could benefit from Dasuquin. If your veterinarian has already recommended Dasuquin, the sooner it is started the more opportunity your pet will have to respond. Your veterinarian may also suggest using Dasuquin as a protective measure. This can be important for maintaining an active life for many dogs, especially large breeds and working dogs of all sizes. Dasuquin may also be used to help support cartilage following joint surgery.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

My dog has been taking a joint health supplement product. How is Dasuquin different?

Dasuquin is a joint health supplement containing the powerful ingredient ASU along with the optimal amount of glucosamine and chondroitin sulfate for your pet. ASU works along with glucosamine and chondroitin sulfate to support your pet’s joints. In fact, cell culture studies have shown that the combination of glucosamine/chondroitin sulfate plus ASU works better than glucosamine/chondroitin sulfate alone. Tea is included for additional wellness support and benefits making Dasuquin the most comprehensive joint health formula available. Try it and see the difference in your best friend.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

My dog’s food contains glucosamine and chondroitin sulfate. Do I still need Dasuquin?

Yes. None of the foods contain the same researched combination of high quality ingredients in Dasuquin. The amount of glucosamine and chondroitin sulfate in dog food is minimal. Even if these diets contained high quality glucosamine and chondroitin sulfate, according to the amounts listed on the labels a dog would need to consume much more than a serving to obtain the amounts found in Dasuquin. In addition, both glucosamine and chondroitin sulfate may degrade when subjected to the heat or extreme pressure in the manufacturing process of commercial dog food.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

What should I look for when giving Dasuquin?

Observe your dog closely, and notice whether your dog seems more comfortable doing those activities he seemed reluctant doing or had some trouble doing previously. Changes in your dog’s comfort level may occur gradually. Allow time for your dog to respond. It may take 4-6 weeks, though some dogs may respond sooner.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

What else can I do for my dog?

Your veterinarian may recommend exercise, which is important for optimal joint function as well as weight control and the overall health of your pet. Joint movement is needed to circulate fluid around the cartilage as well as to bring nutrients and to remove waste products. It has been shown that when joints are immobilized, cartilage structures deteriorate at a rapid rate. You should ask your veterinarian, but in most cases, moderate exercise is recommended. Walking on sand or another soft surface or even swimming will help circulate needed nutrients and reduce excessive stress to the cartilage. It is important not to push your pet but to exercise at a comfortable pace.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

Are there any safety concerns with Dasuquin?

While sensitivity to avocados has been reported in a few dogs, taking Dasuquin tablets is not the same as eating whole avocados. The ASU in Dasuquin has been evaluated in a safety study in dogs, and no adverse effects were noted from administration. There are no known contraindications or known interactions between Dasuquin and any drug or nutritional supplement.

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What strengths and sizes is Dasuquin available in?

Dasuquin is available in two different strengths because one size does not fit all dogs. Dasuquin for Small to Medium Dogs has been optimized for dogs under 60 pounds. Dasuquin for Large Dogs contains a formula optimized for dogs 60 pounds and over. Both formulations are packaged in 84 count and 150 count bottles. The 84 count size is a convenient size for use during the initial 4-6 week loading period, while the 150 count economy size is more cost-effective and is ideal for long-term use. Dasuquin is also available in a formula with MSM (methylsulfonylmethane). Your veterinarian can advise you on which formula is best for your dog.

Dasuquin for Dogs AnswersBack To Dasuquin for Dogs Questions

Where do I purchase Dasuquin?

Dasuquin is available only from your veterinarian. As your pet’s health care professional, your veterinarian is best qualified to decide if Dasuquin may benefit your dog and can monitor your pet’s response, making any adjustments necessary to the administration level.

*Dasuquin® contains FCHG49® Glucosamine, TRH122® Sodium Chondroitin Sulfate, and NMX1000® Avocado/Soybean Unsaponifiables, Nutramax Laboratories® proprietary veterinary researched specifications.

Dasuquin^® for Cats

Dasuquin^® for Cats QuestionsBack to Top

What is Dasuquin for Cats?

What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?

What is ASU, and how does it work?

How do I know if my cat needs Dasuquin?

My cat has been taking a joint health supplement product. How is Dasuquin different?

What should I look for when giving Dasuquin?

My veterinarian mentioned that Dasuquin can be used to help maintain the health of my cat’s bladder. How does this work?

Are there any safety concerns with Dasuquin?

Where do I purchase Dasuquin?

What other products does Nutramax Laboratories, Inc. have for my pet?

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

What is Dasuquin^® for Cats?

Dasuquin from Nutramax Laboratories, Inc. is a joint health supplement for cats that goes beyond standard glucosamine supplements. It contains NMX1000^®* avocado/soybean unsaponifiables (ASU), decaffeinated tea, FCHG49^®* glucosamine hydrochloride, and TRH122^®* low molecular weight chondroitin sulfate in a natural chicken and tuna flavored sprinkle capsule. It is the most complete joint support supplement available.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?

The combination of the trademarked FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate supports cartilage production and helps block enzymes in joints that break down cartilage. These ingredients together have been shown in published studies to protect joint cartilage better than either ingredient alone. A greater than additive effect, known as a “synergistic” effect, on cartilage cells was seen using this glucosamine and low molecular weight chondroitin sulfate together.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

What is ASU, and how does it work?

ASU stands for avocado/soybean unsaponifiables, an ingredient concentrated directly from avocados and soybeans that is used for joint health. ASU has been shown to improve joint function and comfort levels. Studies using cartilage cells have shown that ASU lowers the expression or production of several compounds involved in the process of cartilage breakdown in joints. ASU complements the positive effects of the other active ingredients in Dasuquin. The glucosamine in Dasuquin is synergistic with low molecular weight chondroitin sulfate and has been shown in cartilage cell studies to be synergistic with ASU. Having ASU in the Dasuquin formula is also beneficial as NMX1000^® avocado/soybean unsaponifiables, FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate together were shown in cell studies to be better than the combination of glucosamine and chondroitin sulfate alone at inhibiting expression of several agents involved in the breakdown of cartilage. The highly absorbable tea is rich in antioxidants, which have a positive effect on cartilage as well as on overall body defenses.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

How do I know if my cat needs Dasuquin?

It may be a good time to ask your veterinarian about Dasuquin if you notice that your cat is less eager to jump or play or otherwise appears less mobile. Your veterinarian will examine your cat to determine if he/she could benefit from Dasuquin. If your veterinarian has already recommended Dasuquin, the sooner it is started the more opportunity your pet will have to respond. Your veterinarian may also suggest using Dasuquin as a protective measure. Dasuquin may also be used to help support cartilage following joint surgery.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

My cat has been taking a joint health supplement product. How is Dasuquin different?

Dasuquin is a joint health supplement containing the powerful ingredient ASU along with glucosamine and chondroitin sulfate. ASU works along with glucosamine and chondroitin sulfate to support your pet’s joints. In fact,research has shown that the combination of glucosamine plus ASU works better than glucosamine/chondroitin sulfate alone! Tea is included for additional wellness support and benefits making Dasuquin the most comprehensive joint health formula available. Try it and see the difference in your best friend.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

What should I look for when giving Dasuquin?

Observe your cat closely, and notice whether your cat seems more comfortable doing those activities he/she seemed reluctant doing or had some trouble doing previously. Changes in your cat’s comfort level may occur gradually. Allow time for your cat to respond. It may take 4-6 weeks, though some cats may respond sooner.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

My veterinarian mentioned that Dasuquin can be used to help maintain the health of my cat’s bladder. How does this work?

Some veterinarians may recommend Dasuquin to help maintain urinary bladder health. The inner lining of the bladder wall is protected by a layer, which contains some of the same compounds as are found in cartilage. This layer keeps urine and the waste products contained within it from seeping into and affecting the lining. Since the low molecular weight chondroitin sulfate found in Dasuquin is available to more than just cartilage cells, the bladder may use it to help support this protective layer.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

Are there any safety concerns with Dasuquin?

Dasuquin has been evaluated in a safety study in cats, and no adverse effects were noted from administration. There are no known contraindications or known interactions between Dasuquin and any drug or nutritional supplement.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

Where do I purchase Dasuquin?

Dasuquin is available only from your veterinarian. As your pet’s health care professional, your veterinarian is best qualified to decide if Dasuquin may benefit your cat and can monitor your pet’s response, making any adjustments necessary to the administration level.

Dasuquin for Cats AnswersBack To Dasuquin for Cats Questions

What other products does Nutramax Laboratories, Inc. have for my pet?

In addition to Dasuquin, Nutramax Laboratories, Inc. has other products that may be beneficial to your pet’s health. The natural supplement Welactin^® For Cats provides omega-3 fatty acids to help support joint health and overall wellness (including organ, brain/nervous system, and skin and coat health). In some cases veterinarians may recommend adding Welactin to Dasuquin for additional joint support. Nutramax Laboratories, Inc. also has several products, including Denosyl^®, Marin^®, and the combination product Denamarin^®, to support liver health. Oxstrin^® Optimized Feline helps protect against oxidative stress and supports nutritional status. Proviable^® multi-strain probiotic helps naturally reestablish intestinal health. Ask your veterinarian if your pet may benefit from any of these products, and call us or visit our website for more information.

*Dasuquin® contains FCHG49® Glucosamine, TRH122® Sodium Chondroitin Sulfate, and NMX1000® Avocado/Soybean Unsaponifiables, Nutramax Laboratories® proprietary veterinary researched specifications.

Cosequin^® for Dogs

Cosequin^® for Dogs QuestionsBack to Top

What is Cosequin for Dogs?

What is joint cartilage?

How does Cosequin work?

Is Cosequin superior to other joint health supplements?

I give my dog a food that contains glucosamine and chondroitin sulfate. Do I still need Cosequin?

Can I give a supplement labeled for human use to my dog?

When is the use of Cosequin recommended?

My pet just started Cosequin. What should I notice?

How long does Cosequin take to work?

Should I give Cosequin to all of my dogs?

Are there any side effects?

Should I exercise my dog while he is on Cosequin?

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

What is Cosequin^® for Dogs?

Cosequin is a patented, scientifically researched nutritional supplement dispensed by thousands of veterinarians to help dogs maintain healthy joints. As dogs age, it is common for their joints to become less flexible which impacts their mobility and quality of life. You may have noticed that your dog has difficulty walking up stairs or jumping on the bed. While he used to be eager to play, now he is content to rest. Even at younger ages some dogs are subject to joint health concerns which affect flexibility and mobility. Cosequin contains TRH122^®* chondroitin sulfate, FCHG49^®* glucosamine and manganese ascorbate. These ingredients have been scientifically formulated to support and maintain the health of your dog’s joints. Published studies have shown that the specific combination of ingredients in Cosequin works together to maintain the structure of the cartilage in your dog’s joints while inhibiting the enzymes that break down cartilage. It is very important to note that the published studies on Cosequin do not apply to other brands.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

What is joint cartilage?

Cartilage is a slippery and resilient tissue produced and maintained by its own specialized cells. It cushions the surfaces where two or more bones meet to form a flexible joint. When a dog is in motion there is tremendous pressure on the joint. Cartilage, joint fluid, and underlying bone work together like a shock absorber allowing flexible joint function. Because cartilage lacks a direct blood supply, nutrients must pass into the cartilage from surrounding tissue. These nutrients sustain cartilage cells and provide the components necessary to maintain a healthy cartilage structure. Scientists are not sure about all the factors that cause cartilage breakdown; however, they have discovered enzymes that play a role in the process. With age, injury, or over-activity, the process of breakdown can exceed the process of replacement leading to problems in the joints. These problems result in less flexibility. That’s when it’s time for Cosequin^® which maintains the cartilage structure and inhibits the enzymes that break down cartilage.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

How does Cosequin work?

The exclusive combination of TRH122^® chondroitin sulfate, FCHG49^® glucosamine, and manganese ascorbate in Cosequin works together to maintain the structure of your dog’s joint cartilage while slowing the enzymes that break down cartilage. Glucosamine hydrochloride acts as a building block of cartilage by supplying a key nutrient that keeps cartilage cells healthy and functioning properly. Chondroitin sulfate blocks the enzymes thatbreak down cartilage. Manganese ascorbate is added to help optimize the production of cartilage components. Cosequin has been used since 1992 in animals to maintain joint health. While the ingredients have been used separately, published controlled studies show the patented combination of ingredients in Cosequin is superior to using the ingredients alone.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

Is Cosequin superior to other joint health supplements?

Yes. On the label, different brands may appear to be the same, but unlike drugs, the ingredients in supplements are not equivalent. Cosequin, with its exclusive combination of high purity glucosamine, low molecular weight chondroitin sulfate and manganese ascorbate, is the only glucosamine/chondroitin sulfate supplement that has been shown safe, effective, and bioavailable in peer-reviewed, published, controlled, U.S. veterinary studies. Chondroitin sulfate is a large molecule that is difficult to absorb. Low molecular weight means the particle size of the molecule is smaller and more easily absorbed by the digestive system than other less pure forms of chondroitin sulfate. While the low molecular weight chondroitin sulfate is more expensive, it is supported by published, controlled U.S. clinical studies for efficacy, safety and absorption. Cosequin is manufactured in the United States by Nutramax Laboratories, Inc. following manufacturing standards adopted by the pharmaceutical industry. Each batch of Cosequin is subjected to stringent quality control measures and meets label claim. However, a number of reports including a study published in the Journal of the American Nutraceutical Association showed that up to approximately 80% of glucosamine/chondroitin sulfate brands did not meet their own label claim.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

I give my dog a food that contains glucosamine and chondroitin sulfate. Do I still need Cosequin?

Yes. None of the foods contain the researched combination of high quality ingredients in Cosequin. The amount of glucosamine and chondroitin sulfate in dog food is often minimal. Even if these diets contained high quality glucosamine and chondroitin sulfate, a large-breed dog would need to consume more than the daily requirement of food to obtain the amounts of glucosamine and chondroitin sulfate found in Cosequin DS. In addition, both glucosamine and chondroitin sulfate may degrade when subjected to the heat or extreme pressure in the manufacturing process of commercial dog food.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

Can I give a supplement labeled for human use to my dog?

Many human glucosamine/chondroitin sulfate supplements use substandard ingredients, and, as noted earlier, studies have shown that many do not even meet their own label claim for the ingredients listed on the bottle. With Cosequin each capsule or convenient tasty chewable tablet contains exactly what is stated on the label. These trademarked ingredients have been shown to be safe and effective in pets.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

When is the use of Cosequin recommended?

Early action is always the best advice. Different breeds of dogs age at different rates. With regular check-ups your veterinarian can talk with you about your dog’s aging process. Your veterinarian may discuss weight control, selective use of medications, exercise and the administration of Cosequin. It is important to have your dog examined by your veterinarian if you notice the dog having difficulties climbing stairs, jumping into the car, going for walks or even getting up. Your veterinarian can advise you if Cosequin can help. Your veterinarian may also suggest using Cosequin as a protective measure. This can be important for maintaining an active life for many dogs, especially large breeds and working dogs of all sizes. Cosequin may also be used to help support cartilage following joint surgery.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

My pet just started Cosequin. What should I notice?

Observe your dog closely, and notice whether he seems more comfortable performing everyday activities such as climbing up stairs, going for walks, or even getting up. Most people will observe gradual changes in their dog’s comfort level. In a published survey of over 3,000 veterinarians, over 80% of dogs administered Cosequin improved significantly in their mobility, level of comfort, and attitude. Overall, the veterinarians rated Cosequin as good to excellent.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

How long does Cosequin take to work?

Since Cosequin is a supplement and provides nutrients to maintain your dog’s joint health, it works more gradually than drugs. Improvement on Cosequin can range from gradual to dramatic. Following the administration schedule on the label for your dog’s weight, we recommend an initial administration period of four to six weeks. Some dogs may show a response in a shorter period of time.

Cosequin for Dogs AnswersBack To Cosequin for Dogs Questions

Should I give Cosequin to all of my dogs?

Research in dogs administered Cosequin has shown that if Cosequin is given prior to an injury, the animal returns to normal function much more quickly. In light of this research, Cosequin is recommended to protect cartilage in dogs that are overweight, working breeds, and large breeds, as well as the average “weekend warrior.” In order to gain the protective benefits of Cosequin in healthy animals, a low level of Cosequin may be used. The level for these pets varies, but the suggested maintenance level given every other day may be adequate.

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Are there any side effects?

Cosequin offers unparalleled safety. A safety study in dogs demonstrated no adverse effects of Cosequin administration on blood work parameters, including complete blood count, biochemical, and clotting values. Some dogs may experience a mild gastrointestinal upset such as that which occurs when switching foods. If this is the case, you can try offering Cosequin with a meal.

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Should I exercise my dog while he is on Cosequin?

Exercise is important for optimal joint function as well as weight control for the overall health of your pet. Joint movement is needed to circulate fluid around the cartilage as well as to bring nutrients and to remove waste products. It has been shown that when joints are immobilized, cartilage structures break down at a rapid rate. Consult with your veterinarian, but in most cases, moderate exercise is recommended. Walking on sand or another soft surface or even swimming will help circulate needed nutrients and reduce excessive stress to the cartilage. It is important not to push your pet but to exercise at a comfortable pace.

*Cosequin^® contains FCHG49^® Glucosamine, TRH122^® Sodium Chondroitin Sulfate, Nutramax Laboratories^® proprietary veterinary researched specifications.

Cosequin^® for Cats

Cosequin^® for Cats QuestionsBack to Top

What is Cosequin^® for Cats?

What is joint cartilage?

How does Cosequin work?

Why use Cosequin in my cat?

When should I start giving my cat Cosequin?

My veterinarian mentioned that Cosequin can be used to help support the health of my cat’s bladder. How does this work?

How long does Cosequin take to work?

Is Cosequin superior to other joint health supplements?

What about products that contain perna mussel?

Are there any side effects?

How is Cosequin administered?

Cosequin for Cats Answers

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

What is Cosequin^® for Cats?

Cosequin is a patented, scientifically researched nutritional supplement dispensed by thousands of veterinarians to help cats maintain healthy joints. As cats age, it is common for their joints to become less flexible which impacts their mobility and quality of life. You may have noticed that your cat is less eager to jump to her favorite spot. While she used to prowl and chase “prey”, now she is content to rest. Cosequin contains TRH122^®* low molecular weight chondroitin sulfate, FCHG49^®* glucosamine hydrochloride and manganese ascorbate. These ingredients have been scientifically formulated to support and maintain the health of your cat’s joints. Published clinical studies have shown that the specific combination of ingredients in Cosequin works together to maintain the structure of the cartilage in the joints while inhibiting the enzymes that break down cartilage. It is very important to note that the published clinical studies on Cosequin do not apply to other brands.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

What is joint cartilage?

Cartilage is a slippery and resilient tissue produced and maintained by its own specialized cells. It cushions the surfaces where two or more bones meet to form a flexible joint. Cartilage, joint fluid, and underlying bone work together like a shock absorber allowing flexible joint function. Because cartilage lacks a direct blood supply, nutrients must pass into the cartilage from surrounding tissue. These nutrients sustain cartilage cells and provide the components necessary to maintain a healthy cartilage structure. Scientists are not sure about all the factors that cause cartilage breakdown; however, they have discovered enzymes that play a role in the process. With age, injury, or over-activity, this process of breakdown can exceed the process of replacement leading to problems in the joints. These problems result in less flexibility. That’s when it’s time for Cosequin which maintains the cartilage structure and inhibits the enzymes that break down cartilage.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

How does Cosequin work?

The exclusive combination of TRH122^® low molecular weight chondroitin sulfate, FCHG49^® glucosamine hydrochloride, and manganese ascorbate in Cosequin works together to maintain the structure of your cat’s joint cartilage while slowing the enzymes that break down cartilage. Glucosamine hydrochloride acts as a building block of cartilage by supplying a key nutrient that keeps cartilage cells healthy and functioning properly. Chondroitin sulfate blocks the enzymes that break down cartilage. Manganese ascorbate is necessary to optimize the production of cartilage components. Cosequin has been used since 1992 in animals to maintain joint health. While the ingredients have been used separately, published controlled clinical studies show the patented combination of ingredients in Cosequin is superior to using the ingredients alone. On the label, different brands appear to be the same, but unlike drugs, the ingredients in supplements are not equivalent.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

Why use Cosequin in my cat?

There are not many joint support options available specifically for cats. There are some products used in dogs that are not as safe in cats. Cosequin has been shown to be safe in cats. Cosequin, a nutritional supplement, safely and effectively provides joint cartilage support while maintaining your cat’s comfort level.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

When should I start giving my cat Cosequin?

Early action is always the best advice. With regular checkups your veterinarian can talk with you about your cat’s aging process. Your veterinarian may discuss weight control and the administration of Cosequin to help your cat in her senior years. Whenever you notice limping, stiffness, or a reluctance to jump, it is important to have your cat examined by your veterinarian. Your veterinarian can advise you if Cosequin can help. Joint problems generally get worse with time. When your veterinarian recommends Cosequin, the sooner it is started, the more opportunity your pet will have to respond and return to normal activity.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

My veterinarian mentioned that Cosequin can be used to help support the health of my cat’s bladder. How does this work?

Some veterinarians also recommend Cosequin to help support urinary bladder health. The inner lining of the bladder wall is protected by a layer, which contains some of the same compounds as are found in cartilage. This layer prevents urine and the waste products contained within it from seeping into and damaging the lining. Since the low molecular weight chondroitin sulfate found in Cosequin is available to more than just cartilage cells, the bladder may use it to help support this protective layer.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

How long does Cosequin take to work?

Since Cosequin is a supplement and provides nutrients to maintain your cat’s health, it works more gradually than drugs. Improvement using Cosequin can range from gradual to dramatic. Following the administration schedule on the label, we recommend an initial administration period of 4-6 weeks. Some cats may show an optimal response in a shorter period of time. The long-term maintenance level is one capsule every other day. Administration may be increased at any time depending on your cat’s needs.

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Is Cosequin superior to other joint health supplements?

Yes. Cosequin, with its exclusive combination of high purity glucosamine, low molecular weight chondroitin sulfate and manganese ascorbate, is the only glucosamine/chondroitin sulfate supplement that has been shown safe, effective, and bioavailable in peer-reviewed, published, controlled, U.S. veterinary studies. Chondroitin sulfate is a large molecule that is difficult to absorb. Cosequin is the only brand that uses the high purity, TRH122^® low molecular weight chondroitin sulfate that has been studied for absorption. Lower molecular weight means the particle size of the molecule is smaller and more easily absorbed by the digestive system than other less pure forms of chondroitin sulfate. While this highly pure form of chondroitin sulfate is more expensive, it is the only one supported by published, controlled U.S. clinical studies for efficacy, safety and absorption. Cosequin is manufactured in the United States by Nutramax Laboratories, Inc. following manufacturing standards adopted by the pharmaceuical industry. Each batch of Cosequin is subjected to stringent quality control measures and meets label claim, while a study published in the Journal of the American Nutraceutical Association showed that over 80% of glucosamine/chondroitin sulfate brands did not meet their own label claim.

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What about products that contain perna mussel?

Supplements that contain perna mussel (or greenlipped mussel) have not been subjected to the same type of research as Cosequin. There is no published evidence that the nutrients in perna mussel products have the same capacity to maintain the health of cartilage while protecting it from destructive enzymes. A consumer should be cautioned about buying a product unless the specific brand has been subjected to published, controlled, peer-reviewed clinical studies.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

Are there any side effects?

Cosequin offers unparalleled safety. A safety study in cats demonstrated no adverse effects of Cosequin administration on blood work parameters, including complete blood count, biochemical and clotting values. Some cats may experience a mild gastrointestinal upset such as may occur when switching foods, but this usually will resolve itself.

Cosequin for Cats AnswersBack To Cosequin for Cats Questions

How is Cosequin administered?

Cosequin Capsules for Cats contain a flavored powder. The capsule can be opened and contents mixed with or sprinkled over the food. The capsule may instead be “pilled” if more convenient.

*Cosequin^® contains FCHG49^® Glucosamine, TRH122^® Sodium Chondroitin Sulfate, Nutramax Laboratories^® proprietary veterinary researched specifications.

Cosequin^® Equine Products

Cosequin^® Equine QuestionsBack to Top

What is Cosequin ASU?

What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?

What is ASU?

Why is MSM included in the formula?

What is meant by broad spectrum?

How is Cosequin ASU different from other supplements?

Are there any safety concerns with Cosequin ASU?

Can Cosequin ASU be given to a pregnant mare?

Can Cosequin ASU be used on a competition day?

What response should I see in my horse when giving Cosequin ASU?

My veterinarian has also recommended an injectable joint product. Why?

Cosequin^® Equine Powder QuestionsBack to Top

What is Cosequin Equine Powder?

How does Cosequin Equine Powder work?

When should I start giving my horse Cosequin?

How do I administer the powder to my horse?

Is Cosequin cost effective?

Where can I buy Cosequin?

When examining the label of other products they may appear to contain the same ingredients as Cosequin Equine Powder, but do they?

Cosequin®Optimized & Optimized with MSM QuestionsBack to Top

What is an Optimized Formula and should my horse be given this?

I am currently giving my horse Original Cosequin Equine Powder. Should I switch to the Cosequin Optimized?

Why does one of the Cosequin Optimized formula contain MSM?

Cosequin^®HA+ASU TreatsBack to Top

What are Cosequin HA+ASU Treats?

What About Me and My Pets?Back to Top

When I’m riding I put stress on my own joints. Is there a Nutramax Laboratories,Inc. product for me?

Does Nutramax Laboratories, Inc. make a Cosequin product for my cat or dog?

Cosequin Equine AnswersBack to Cosequin Equine Questions

What is Cosequin^® ASU?

Cosequin ASU from Nutramax Laboratories, Inc. is a superior joint health supplement in a tasty powder for horses that goes beyond standard joint supplements. It contains NMX1000^®* avocado/soybean unsaponifiables (ASU), MSM (methylsulfonylmethane), FCHG49^®* glucosamine hydrochloride, and TRH122^®* low molecular weight chondroitin sulfate. With this combination of active ingredients, Cosequin ASU is the most complete joint support supplement available for horses.

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What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?

The combination of the trademarked FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate supports cartilage production and inhibits joint enzymes that break down cartilage.These two ingredients together have been shown to protect joint cartilage better than either ingredient alone. A greater than additive effect, known as a “synergistic” effect, on cartilage cells was seen using Nutramax Laboratories, Inc. specific glucosamine and low molecular weight chondroitin sulfate together.

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What is ASU?

ASU stands for avocado/soybean unsaponifiables, derived from avocados and soybeans. Studies using cartilage cells have shown that it lowers the expression or production of several compounds involved in the process of cartilage breakdown in joints. ASU complements the positive effects of the glucosamine and chondroitin sulfate in Cosequin^® ASU. The glucosamine in Cosequin ASU is synergistic with low molecular weight chondroitin sulfate and has been shown in cartilage cell studies to be synergistic with ASU. Having ASU in the Cosequin ASU formula is especially beneficial as NMX1000^® avocado/soybean unsaponifiables, FCHG49^® glucosamine hydrochloride and TRH122^® low molecular weight chondroitin sulfate together were shown in cell studies to be more effective than the combination of glucosamine and chondroitin sulfate alone at inhibiting expression of several agents involved in the breakdown of cartilage.

Cosequin Equine AnswersBack to Cosequin Equine Questions

Why is MSM included in the formula?

Although clinical data on MSM is limited, many veterinarians and trainers recommend the use of MSM in the management of joint health. MSM is an organic source of sulfur, a compound used by cartilage. MSM with ASU, glucosamine hydrochloride, and chondroitin sulfate provides a joint health supplement formula for those individuals that would like to additionally supplement with high purity MSM.

Cosequin Equine AnswersBack to Cosequin Equine Questions

What is meant by broad spectrum?

Broad spectrum means that the ingredients support cartilage health via many pathways. As mentioned earlier, the ingredients inhibit compounds and enzymes in the joint that contribute to cartilage breakdown while also supporting cartilage production.

Cosequin Equine AnswersBack to Cosequin Equine Questions

How is Cosequin ASU different from other supplements?

Cosequin ASU contains the ingredient ASU along with the optimal amounts of glucosamine and chondroitin sulfate that your horse needs. ASU works along with glucosamine and chondroitin sulfate to support your horse’s joints. In fact, the combination of glucosamine/chondroitin sulfate plus ASU has been shown to work better in cartilage cell studies than the combination of glucosamine/chondroitin sulfate alone. Cosequin ASU has the further addition of high purity MSM. Some veterinarians suggest using MSM to help manage joint health.

Cosequin Equine AnswersBack to Cosequin Equine Questions

Are there any safety concerns with Cosequin ASU?

Cosequin ASU has been evaluated in a safety study in horses, and no adverse effects were noted from administration. There are no known contraindications or known interactions between Cosequin ASU and any drug or nutritional supplement.

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Can Cosequin ASU be given to a pregnant mare?

No studies have been completed that specifically address the use of Cosequin ASU during pregnancy. Use of Cosequin ASU during pregnancy should be an individual decision made in consultation with your veterinarian.

Cosequin Equine AnswersBack to Cosequin Equine Questions

Can Cosequin ASU be used on a competition day?

Cosequin ASU contains supplement ingredients for assisting joint health. It is best to check with your appropriate authority regarding its regulations or restrictions on supplement usage.

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What response should I see in my horse when giving Cosequin ASU?

Prior to starting Cosequin ASU, you may have noticed unevenness of gait, reluctance to take or change a lead, or shortness of stride, which may be early indicators of cartilage breakdown. After starting administration with Cosequin ASU, observe your horse closely, and notice whether your horse becomes more comfortable doing those activities he/she seemed reluctant doing or had some trouble doing previously. Changes in your horse’s comfort level may occur gradually. Please allow time for your horse to respond. As noted above, it may take 2-4 weeks to see improvement, though some horses may respond sooner.

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My veterinarian has also recommended an injectable joint product. Why?

Cosequin ASU helps to minimize ongoing joint wear and tear by supporting joint cartilage production and by inhibiting enzymes and mediators involved in cartilage breakdown. Horses will usually respond to Cosequin ASU within 2-4 weeks, sooner in some horses. In some cases in which a more immediate response is desired, your veterinarian may initially recommend an injectable product.

*Cosequin^® ASU contains FCHG49^® Glucosamine, TRH122^® Sodium Chondroitin Sulfate, and NMX1000^® Avocado/Soybean Unsaponifiables, Nutramax Laboratories^® proprietary veterinary researched specifications.

Cosequin Equine Powder Answers

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

What is Cosequin^®Equine Powder?

Cosequin is an exclusive formula of three important ingredients: TRH122^®* low molecular weight chondroitin sulfate, FCHG49^®* glucosamine hydrochloride,and manganese ascorbate. These ingredients have been scientifically formulated to support and maintain the health of your horse’s joints. Published studies have shown that the specific combination of ingredients in Cosequin helps to maintain the structure of the cartilage while inhibiting the enzymes that break down cartilage. Cosequin is the only glucosamine/chondroitin sulfate brand that has been shown safe, bioavailable and effective in horses in published studies.

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

How does Cosequin^®Equine Powder work?

Cartilage is a slippery and resilient tissue produced and maintained by its own specialized cells. It cushions the surfaces where two or more bones form a flexible joint. Cartilage, joint fluid, and underlying bone work together like a shock absorber allowing flexible joint function. Because cartilage lacks a direct blood supply, nutrients must pass into the cartilage from surrounding tissue. These nutrients sustain cartilage cells and provide the components necessary to maintain a healthy cartilage structure. With age, injury, or over-activity, cartilage cannot maintain the proper balance in metabolic activity, and breakdown of cartilage can exceed the process of cartilage production. That’s when it’s time for Cosequin. The components of Cosequin work both to synergistically enhance the synthesis of cartilage matrix as well as to inhibit the enzymes that break down cartilage, thus helping to restore balance. Glucosamine hydrochloride acts as a building block of cartilage by supplying a key nutrient that keeps cartilage cells healthy and functioning properly. Chondroitin sulfate blocks the enzymes that break down cartilage.

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

When should I start giving my horse Cosequin^®?

Early action is always the best advice. Many horse owners can detect subtle changes in their horse’s gait when breakdown of cartilage is just beginning. Unevenness in gait, reluctance to take or change a lead or shortness of stride are all early warnings of cartilage breakdown. Your first step is to have your horse examined by your veterinarian. Your veterinarian will advise you if Cosequin can help. By using Cosequin early, you may be able to offset long-term problems. Published research has reported improvement in some horses as early as two weeks.

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

How do I administer the powder to my horse?

Detailed instructions are contained in the package inserts. The recommended initial administration period is two to four weeks. Following the initial administration period, the amount of powder can be reduced to an economical maintenance schedule. Once consistent improvement has been seen, in some cases these maintenance levels can be further reduced to an every other day administration. To meet the demands prior to and during an event or strenuous outing, the administration can be increased back to the initial amount. The maintenance level may also be used daily or every other day on healthy horses to help support their joints.

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

Is Cosequin^® cost effective?

Yes! As your horse’s performance improves, the daily amount of Cosequin may be reduced to an economical maintenance level. This level may be as low as one scoop per day or every other day.

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

Where can I buy Cosequin^®?

While Cosequin is not a drug and there is no need for a prescription, it is important to consult with your veterinarian about your horse’s health, as well as the selection of the correct supplement. For more information on Cosequin Equine Powder and where to purchase, call Nutramax Laboratories, Inc. at 1-800-925-5187. Nutramax Laboratories, Inc. also has customer service representatives to answer your questions about Cosequin.

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

When examining the label of other products they may appear to contain the same ingredients as CosequinEquine Powder, but do they?

Many products try to compare to Cosequin, but there is no generic equivalent. Chondroitin sulfate is a large molecule that is difficult to absorb. Cosequin is the only brand that uses the TRH122^®* low molecular weight chondroitin sulfate, which has been evaluated and shown bioavailable. Low molecular weight means the particle size of the molecule is smaller and more easily absorbed by the digestive system than other less pure forms of chondroitin sulfate. While this form of chondroitin sulfate is more expensive, it is the only one supported by published, controlled U.S. clinical studies for efficacy, safety and bioavailability. Other products that are labeled to contain chondroitin sulfate may actually use ground up cartilage or other less pure material. Many other products contain ingredients from sources that may not maintain strict quality control standards for purity and quality. Cosequin Equine Powder also contains FCHG49^®* glucosamine hydrochloride, which is greater than 99% pure. Glucosamine hydrochloride delivers significantly more bioavailable glucosamine than an equivalent amount of glucosamine sulfate. In summary, the purity and bioavailability of Cosequin’s trademarked ingredients, guaranteed to be as stated on the label, make Cosequin the best choice! Cosequin contains FCHG49^® glucosamine hydrochloride and TRH122^® low molecular weight sodium chondroitin sulfate, Nutramax Laboratories^® exclusive veterinary researched specifications.

Cosequin^®Optimized & Optimized with MSM Answers

Cosequin Optimized & Optimized with MSM AnswersBack to Cosequin Equine Questions

What is an Optimized Formula and should my horse be given this?

Cosequin^®Optimized is the original researched formula now with higher levels of active ingredients per scoop in a tasty powder. Current opinion suggests that horses involved in heavy activity may need higher levels of glucosamine. Cosequin Optimized provides 14,400 mg of glucosamine hydrochloride (based on 2 scoops loading administration) vs. original Cosequin’s 10,800 mg (based on 6 scoops loading administration).

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

I am currently giving my horse Original Cosequin^®Equine Powder. Should I switch to the Cosequin Optimized?

If you are happy with the results you are seeing using the Original Cosequin Concentrated Powder then there is no reason to change. If your horse has an intense competition schedule you may want to switch to Cosequin Optimized for the increased levels of active ingredients.

Cosequin Equine Powder AnswersBack to Cosequin Equine Questions

Why does one of the Cosequin^®Optimized formula contain MSM?

MSM is an organic source of sulfur, a compound used by cartilage. Some veterinarians suggest using MSM to help manage joint health. Cosequin Optimized with MSM for horses contains 10,000 mg of MSM (2 scoops). For those wishing to additionally supplement MSM, Cosequin Optimized with MSM offers a convenient, cost-effective way to administer MSM along with the proven ingredients in Cosequin Optimized.

Cosequin^®HA+ASU Treats Answer

Cosequin^®HA+ASU Treats AnswersBack to Cosequin Equine Questions

What are Cosequin^®HA+ASU Treats?

Cosequin HA+ASU Treats provide a high quality hyaluronic acid (HA) along with avocado/soybean unsaponifiables (ASU) for joint health. HA is a major component of synovial fluid, the substance that helps keep joints lubricated. ASU has been shown in cartilage cell studies to lower the expression or production of several compounds involved in the process of cartilage breakdown in joints. Cosequin HA+ASU Treats offer a convenient way to add HA and ASU to your current Cosequin joint health regimen. Cosequin HA+ASU Treats may be combined with any of the other Cosequin equine powder products to help support joint health in your horse.

What About Me and My Pets? Answers

What About Me and My Pets? AnswersBack to Cosequin Equine Questions

When I’m riding I put stress on my own joints. Is there a Nutramax Laboratories,Inc. product for me?

Yes, Nutramax Laboratories, Inc. makes Cosamin^®ASU for Active People, the combination of ASU, glucosamine hydrochloride and low molecular weight chondroitin sulfate. CosaminASU is the most complete and comprehensive joint support supplement available. ASU complements the positive effects of the other ingredients in CosaminASU. Having ASU in the CosaminASU formula is also beneficial as ASU, glucosamine hydrochloride, and chondroitin sulfate together were shown in cell culture studies to work better than glucosamine and chondroitin sulfate alone.

What About Me and My Pets? AnswersBack to Cosequin Equine Questions

Does Nutramax Laboratories, Inc. make a Cosequin^® product for my cat or dog?

Yes, Cosequin is available in five formulations, each designed for specific needs depending on the overall health of your pet: Cosequin DS, Cosequin Multi, Cosequin Bonelets^® Hip and Joint Support, Cosequin Bonelets^® Hip and Joint Support Plus, and Cosequin for Cats.

Denosyl^®

Denosyl QuestionsBack to Top

What formulations of Denosyl are available?

How much Denosyl should I give my pet?

What should I look for when I give Denosyl?

How will my veterinarian monitor my pet's response while on Denosyl?

Are there any side effects?

Can Denosyl be used with other products?

Are other brands the equivalent to Denosyl?

Since S-Adenosylmethionine is made from methionine, should I give my pet methionine?

Denosyl AnswersBack to Denosyl Questions

What formulations of Denosyl are available?

Denosyl is available in two formulations for your convenience: Original enteric-coated tablets for cats and dogs and now New tasty, scored chewable tablets for dogs for easy administration.

Denosyl AnswersBack to Denosyl Questions

How much Denosyl should I give my pet?

Your veterinarian will advise you as to the amount to initially administer. Depending on your pet’s response and status, your veterinarian may eventually adjust this amount to meet your pet’s individual needs. Remember, Denosyl enteric-coated tablets should not be broken. When increasing or decreasing their administration, adjustments should be done in full tablet increments. Some pets are given Denosyl only for a short period of time, while Denosyl may be used longer in other animals.

Denosyl AnswersBack to Denosyl Questions

What should I look for when I give Denosyl?

While response varies, owners may note an improvement in their pet’s appetite, activity, and attitude.

Denosyl AnswersBack to Denosyl Questions

How will my veterinarian monitor my pet's response while on Denosyl?

Your veterinarian will likely recommend follow-up examinations, blood work, and/or other laboratory work to check on how well your pet is doing with Denosyl and how it may be helping to improve your pet’s liver function.

Denosyl AnswersBack to Denosyl Questions

Are there any side effects?

Denosyl has been shown to be well-tolerated by both dogs and cats with a wide margin of safety.

Denosyl AnswersBack to Denosyl Questions

Can Denosyl be used with other products?

Yes, your veterinarian may recommend combining Denosyl with other products and/or dietary modifications. One such product is called Marin^®, which can be administered with Denosyl for additional liver support. There are no known adverse interactions of Denosyl with drugs or other supplements. Denosyl may even protect against negative effects on the liver caused by some medications.

Denosyl AnswersBack to Denosyl Questions

Are other brands the equivalent to Denosyl?

While other S-Adenosylmethionine (SAMe) products for humans are available in health food stores and over-the-counter in pharmacies, there can be a significant variance in product quality and activity levels of SAMe. Denosyl is the only brand shown to be safe and effective for pets in published US veterinary research studies. Denosyl is a nutritional product produced under manufacturing standards similar to those used by the pharmaceutical industry.

Denosyl AnswersBack to Denosyl Questions

Since S-Adenosylmethionine is made from methionine, should I give my pet methionine?

Administration of methionine is not recommended. Providing high levels of methionine to pets with liver compromise may not increase the production of natural S-Adenosylmethionine and has been shown in some cases to increase liver damage.

Denamarin^®

Denamarin QuestionsBack to Top

What formulations of Denamarin are available?

How much Denamarin should I give my pet?

How will I know if Denamarin is helping my pet?

Are there any side effects?

Can Denamarin be used with other products?

Are other brands the equivalent to Denamarin?

Since one of the actives in Denamarin is S-Adenosylmethionine (SAMe) and that is made from methionine, should I give my pet methionine?

Denamarin AnswersBack to Denamarin Questions

What formulations of Denamarin are available?

Denamarin is available in two formulations for your convenience: Original enteric-coated tablets for cats and dogs and now New tasty, scored chewable tablets for dogs for easy administration.

Denamarin AnswersBack to Denamarin Questions

How much Denamarin should I give my pet?

Your veterinarian will advise you as to the amount to initially administer. Depending on your pet’s response and status, your veterinarian may eventually adjust this amount to meet your pet’s individual needs. Remember, Denamarin enteric-coated tablets should not be broken. When increasing or decreasing their administration, adjustments should be done in full tablet increments. Some pets are given Denamarin only for a short period of time, while Denamarin may be used longer periods of time in other animals.

Denamarin AnswersBack to Denamarin Questions

How will I know if Denamarin is helping my pet?

Your veterinarian will likely recommend follow-up examinations, blood work, and/or other laboratory work to check on how well your pet is doing with Denamarin and how it may be helping to improve your pet’s liver function. At home, watch for improvements in attitude, appetite, and activity level.

Denamarin AnswersBack to Denamarin Questions

Are there any side effects?

The active ingredients in Denamarin have been shown to be well-tolerated by both dogs and cats with a wide margin of safety.

Denamarin AnswersBack to Denamarin Questions

Can Denamarin be used with other products?

Yes, your veterinarian may recommend combining Denamarin with other products, like Marin^®, and/or dietary modifications. Combining Marin with Denamarin provides added levels of silybin along with vitamin E and zinc for those patients that may benefit from additional liver support. There are no known interactions of Denamarin with drugs or other supplements.

Denamarin AnswersBack to Denamarin Questions

Are other brands the equivalent to Denamarin?

While other S-Adenosylmethionine and silybin products for humans are available in health food stores and over-the-counter in pharmacies, there can be a significant variance in product quality and tablet strengths. Denamarin’s active ingredients individually have been shown to be safe and effective for both dogs and cats in published research studies. Denamarin contains a specific silybin shown to provide better bioavailability in dogs compared to the standardized milk thistle commonly available in health food stores and over-the-counter in pharmacies.

Denamarin AnswersBack to Denamarin Questions

Since one of the actives in Denamarin is S-Adenosylmethionine (SAMe) and that is made from methionine, should I give my pet methionine?

Administration of methionine is not recommended. Providing high levels of methionine to pets with liver compromise may not increase the production of natural S-Adenosylmethionine and has been shown in some cases to increase liver damage.

Marin^®

Marin QuestionsBack to Top

What is Marin?

How can Marin help my pet's liver?

How will I know if Marin is helping my pet?

How do I give Marin to my pet and how much should I give?

Are there any interactions between the ingredients in Marin and other products?

Since one of the actives in Denamarin is SAMe and that is made from methionine, should I give my pet methionine?

Do the ingredients in Marin cause any side effects?

Marin^® Answers

Marin AnswersBack to Marin Questions

What is Marin^®?

Marin is a combination of ingredients providing a comprehensive approach to liver support. The active ingredients in Marin For Dogs are silybin, vitamin E, and zinc, while the active ingredients in Marin For Cats are silybin and vitamin E.

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How can Marin help my pet's liver?

Silybin is the most active part of an extract known as silymarin. Silybin/silymarin has been shown to support liver function by acting as an antioxidant. This means that it helps to counteract or protect against the harmful effects on the liver of “reactive” oxygen compounds. Silybin helps the flow of bile through the liver. Bile contains digestive enzymes along with other substances and aids in digestion and absorption of nutrients from your pet’s diet. Additionally, silybin may support levels of a substance called glutathione, which is the liver’s major “detoxifying” agent. Vitamin E is an antioxidant that has also been shown to help protect liver function. Zinc supplementation may be beneficial in dogs with long-term decreased liver function as these dogs often have low liver zinc levels. Zinc also has antioxidant effects. Zinc participates in many enzymatic reactions within the body, and any deficiency may have harmful effects. Zinc is not in Marin For Cats as deficiencies have not been noted in cats.

Marin AnswersBack to Marin Questions

How will I know if Marin is helping my pet?

Your veterinarian will likely recommend follow-up examinations, blood work, and/or other laboratory work to check on how well your pet is doing with Marin and how it is helping your pet’s liver function. At home, watch for improvements in attitude, appetite, and activity level.

Marin AnswersBack to Marin Questions

How do I give Marin to my pet and how much should I give?

Marin For Dogs is formulated in a tasty chewable tablet that may be given as a treat. Marin For Dogs tablets are scored, which allows for easier splitting of tablets as recommended in the administration guide. Marin For Dogs is available in two convenient strengths: one for small to medium dogs and one for large dogs. Marin For Cats is available as a small flavored tablet.

Marin AnswersBack to Marin Questions

How long should I continue to give Marin?

Marin is often given for an extended time to continue the benefits to your pet’s health. Based on your pet’s response, your veterinarian will provide you with specific advice on how long your pet needs to take Marin.

Marin AnswersBack to Marin Questions

Are there any interactions between the ingredients in Marin and other products?

There are no known interactions between Marin’s ingredients and any drug or other supplement. In some cases your veterinarian may recommend giving Marin with a product known as Denosyl^® or Denamarin^®. If you have any concerns or questions regarding interactions with Marin, check with your veterinarian. For more information on Denamarin or Denosyl, please see their FAQ section on this page or click on the “Products” tab at the top of this page to view the “Liver Health” products.

Marin AnswersBack to Marin Questions

Do the ingredients in Marin cause any side effects?

There are no known side effects with silybin/silymarin in dogs or cats. Vitamin E is also well-tolerated in recommended amounts. Zinc is usually well-tolerated when given in recommended amounts, though occasionally gastrointestinal upset may be seen. Tto minimize the possibility of any zinc sensitivity in some dogs, it is recommended that Marin For Dogs be given on a full stomach. There are no known contraindications to the use of the ingredients in Marin.

Proviable^® for Dogs and Cats

Proviable DC QuestionsBack to Top

What are direct-fed microbials?

What are prebiotics?

What is Proviable^®?

When would Proviable^® products be administered?

When should I see an improvement in my pet’s condition?

Why do I need Proviable when there are direct-fed microbials in my pet’s food?

Are other brands of probiotic products equivalent to Proviable?

Can I give my pet yogurt instead of Proviable?

Can Proviable products be given with other medications?

Are there any safety concerns or side effects with Proviable products?

How should the Proviable products be stored?

Proviable DC AnswersBack to Proviable DC Questions

What are direct-fed microbials?

Direct-fed microbials are beneficial live bacteria that when ingested help to support the pet’s intestinal and overall health. Direct-fed microbials have certain properties that allow them to compete with harmful bacteria in the intestines, stimulate the immune system, and digest nutrients. Direct-fed microbials are the good bacteria that support intestinal health.

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What are prebiotics?

Prebiotics are complex carbohydrates that can be used as a food source for the direct-fed microbials, especially within the large intestine. This helps to support the growth of the direct-fed microbials within the intestinal tract and therefore helps them to compete against the harmful bacteria for colonization of the intestines.

Proviable DC AnswersBack to Proviable DC Questions

What is Proviable^®?

Proviable products from Nutramax Laboratories, Inc. are multi-strain direct-fed microbial products that also contain prebiotics. There are two formulations: Proviable-KP paste and Proviable-DC capsules. Both formulations contain billions of seven strains of direct-fed microbial microorganisms with two prebiotics; the Proviable-KP paste also contains ingredients to firm loose stools.

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When would Proviable^® products be administered?

Proviable-KP paste and Proviable-DC capsules can be administered when your pet experiences soft stool due to an intestinal imbalance. Proviable-KP is a tasty paste that can be given orally to the pet to help form the stools while both the paste and the capsules help to reestablish healthy intestinal balance. The Proviable-DC capsules can also be given during and after antibiotic therapy and before stressful conditions to help to decrease intestinal imbalance. They can be used long-term as recommended by your veterinarian for certain gastrointestinal conditions.

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When should I see an improvement in my pet’s condition?

For a sudden diarrhea in which the pet otherwise appears normal, the Proviable-KP paste should be administered for 48-72 hours to help to form the stools; however some pets may respond in a shorter period of time. The Proviable-DC capsules should be continued after the stools have started to form, as recommended by your veterinarian. If no improvement is noted, or if your pet is not eating or is vomiting, please contact your veterinarian as soon as possible.

Proviable DC AnswersBack to Proviable DC Questions

Why do I need Proviable when there are direct-fed microbials in my pet’s food?

Direct-fed microbials that are supplied in pet foods may or may not be live when ingested by the pet due to the manufacturing processes of the food and therefore may be ineffective. In addition, there may not be sufficient numbers of the direct-fed microbials to elicit a response, and the strains included in the food may not have beneficial properties. Proviable products in comparison provide a guaranteed concentration of live bacteria and provide multiple beneficial strains.

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Are other brands of probiotic products equivalent to Proviable^®?

Quality of probiotic products has been and continues to be an issue in the veterinary market. Some products may not contain live probiotic microorganisms or may not contain high enough numbers of the direct-fed microbials to help support intestinal health. Plus, not all of these products contain the most beneficial strains of direct-fed microbials. Proviable products on the other hand do contain live direct-fed microbials in high numbers and are quality tested to meet label claims.

Proviable DC AnswersBack to Proviable DC Questions

Can I give my pet yogurt instead of Proviable^®?

Yogurt products may contain direct-fed microbials but not usually at concentrations necessary to help populate the intestinal tract of the dog or cat in order to elicit a beneficial response, especially during times of imbalance. Furthermore, the probiotic species in yogurts may not be live or contain the most beneficial strains for dogs and cats.

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Can Proviable products be given with other medications?

The administration of the paste should be separated by 1-2 hours from other medications. The Proviable-DC capsules should not be given at the same time as antibiotic medications for full effectiveness of the antibiotics; therefore it is best to separate the administration times by 1-2 hours.

Proviable DC AnswersBack to Proviable DC Questions

Are there any safety concerns or side effects with Proviable products?

Direct-fed microbials should be administered based on the recommendation of your veterinarian. They are not recommended for pets that are critically ill or that have a suppressed immune system, or in animals that are severely dehydrated or vomiting. There are no known side effects with direct-fed microbials when administered as recommended by your veterinarian. The Proviable-KP paste should only be used for 48-72 hours unless directed otherwise by your veterinarian, as potentially constipation could result with prolonged use at higher than recommended doses.

Proviable DC AnswersBack to Proviable DC Questions

How should the Proviable products be stored?

The direct-fed microbials in Proviable products are microencapsulated to ensure viability with storage at room temperature, not to exceed 77° F, for two years. The expiration dates are found on the packaging. If there is concern about storage at temperatures above 77° F, the Proviable products can be stored in the refrigerator as long as they are not frozen.

Proviable^®-RB

Proviable-RB QuestionsBack to Top

What makes Proviable-RB different from other brands of probiotic products?

Why do I need to use Proviable-RB?

How does Proviable-RB work?

When should I expect to see results?

How long should my rabbit use Proviable-RB?

Why would I choose paste over powder?

Why are there significant levels of fiber in Proviable-RB?

What is a cecotroph?

Is Proviable-RB paste flavored?

Can I mix Proviable-RB powder with food or juice?

Proviable-RB AnswersBack to Proviable-RB Questions

What makes Proviable-RB different from other brands of probiotic products?

• Proviable-RB contains guaranteed numbers in the billions (with powder plus paste daily administration) of live probiotic microorganisms. Specifically it contains the Enterococcus faecium strain found most often in the intestinal tract of rabbits. Additionally, Proviable-RB paste contains high levels of fiber to improve intestinal motility and encourage normal levels of cecotroph activity. Proviable-RB powder contains electrolytes and vitamins to maintain hydration.
• Some probiotic products may not contain live microorganisms or may not contain the right type or right amount of microorganisms to restore intestinal health.

Proviable-RB AnswersBack to Proviable-RB Questions

Why do I need to use Proviable-RB?

• Proviable-RB helps to restore intestinal function and microfloral balance after imbalances have occurred due to:
• Stress
• Not eating
• Antibiotic use
• A high starch feed ration or an incomplete diet

Proviable-RB AnswersBack to Proviable-RB Questions

How does Proviable-RB work?

The Enterococcus faecium probiotic in Proviable-RB help to compete with harmful bacteria in the intestines and promote balance of the beneficial microflora.

The two dual-purpose prebiotics help to encourage the growth of the beneficial microorganisms in the lower intestinal tract and provide a non-digestible carbohydrate source (fiber).

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When should I expect to see results?

Consult your veterinarian if your pet’s condition does not improve within 24 to 48 hours.

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How long should my rabbit use Proviable-RB?

Proviable-RB paste and powder should be given according to the administration guidelines on the package or as directed by your veterinarian.

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Why would I choose paste over powder?

Proviable-RB Paste helps support short-term intestinal microfloral imbalance, normalize intestinal motility and function and assist appetite.

Proviable-RB Powder helps improve intestinal microfloral imbalance and helps maintain hydration. The powder can be used in conjunction with the paste short-term and alone long-term.

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Why are there significant levels of fiber in Proviable-RB?

Higher fiber content helps to improve intestinal motility and function while encouraging normal levels of cecotroph activity.

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What is a cecotroph?

A cecotroph or cecal pellet is a special bacterial and nutrient-rich feces produced and consumed by rabbits to maintain intestinal health. Production of cecotrophs occurs mainly at night; therefore, they are often-times referred to as “night feces”.

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Is Proviable-RB paste flavored?

Yes, tasty Proviable-RB paste is naturally and artificially carrot flavored.

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Can I mix Proviable-RB powder with food or juice?

The powder can be mixed with 50mL water and administered daily through the water bottle or orally in a syringe. For alternate methods of administration, please contact your veterinarian.

Welactin^®

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What is Welactin?

What are Omega-3 fatty acids?

How can Welactin help my pet?

What changes should I expect to see in my dog or cat with Welactin?

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What is Welactin^®?

Welactin is a specially prepared fish oil manufactured to maintain a high content of Omega-3 fatty acids.

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What are Omega-3 fatty acids?

Specific fatty acids known as "Omega-3 fatty acids" are the "good health" fatty acids. The two predominant long chain Omega-3 fatty acids are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

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How can Welactin help my pet?

Omega-3 fatty acids help support many systems in the body, including skin & coat health, kidney function, brain and overall nervous system health, and the immune system.

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What changes should I expect to see in my dog or cat with Welactin?

While many of Welactin’s important functions are at work inside your pet’s body, you may notice an improvement in your pet’s activity level, attitude, appetite, alertness, and general appearance.