Released: 8/20/2007

More Support for Using Glucosamine Hydrochloride and Chondroitin Sulfate in the Management of Joint Health

Edgewood, MD: Nutramax Laboratories, Inc. is pleased to announce results of an in vitro study* providing further evidence that the combination of FCHG49®** glucosamine hydrochloride and TRH122®** low molecular weight chondroitin sulfate, as found in Cosequin® and the new product Dasuquin®, protects joint health. Also noted were the potential benefits of the compounds’ use in animals with healthy cartilage.

The study from researchers at Michigan State University, published in the July issue of the American Journal of Veterinary Research, mimicked cartilage conditions as when a joint is under stress, as previous studies have done, but cultured the cartilage for two weeks, a longer period of time than most other studies had used. Results showed that the glucosamine and chondroitin sulfate, at concentrations comparable to those able to be obtained in the body, were effective at inhibiting expression of agents involved in cartilage breakdown and at stimulating cartilage production. The study then went a step further and demonstrated that the glucosamine and chondroitin sulfate combination was also effective under normal cartilage conditions, which provides a rationale for administration in healthy animals.

“These results show once again that our specific combination of ingredients supports and protects joint cartilage,” said Carmelita G. Frondoza, PhD, director of Research and Development at Nutramax Laboratories, Inc. “This study provides support for their use in healthy animals, such as working and sporting dogs plus large breeds, to help protect the joints,” added Barbara Eves, DVM, senior manager of Scientific Communications.

The joint health supplement product Dasuquin combines Cosequin’s FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate with an innovative supplement agent, avocado/soybean unsaponifiables (ASU). Dasuquin is supplied as tasty chewable tablets in Small to Medium Dogs and Large Dogs strengths. Additionally, each size of Dasuquin can be purchased in a formulation with methylsulfonylmethane (MSM). Dasuquin for Cats is available in natural chicken and tuna flavored capsules. To learn more about Dasuquin, contact Nutramax Laboratories, Inc. at 1.800.925.5187 or go to

About Nutramax Laboratories, Inc.:
From the makers of Cosequin®, the #1 veterinarian-recommended joint health supplement brand***, comes Dasuquin®, the next generation in joint health support. Other products include Denosyl®, Marin®, and the new combination product Denamarin™ for hepatic support; Welactin®, to help support overall wellness; Oxstrin® for maintenance of oxidative balance in dogs; Consil® Dental and Consil® Orthopedic synthetic bone graft particulate; and CoMal® Q10. For more information, visit

*Chan PS, Caron JP, Orth MW. Effects of glucosamine and chondroitin sulfate on bovine cartilage explants under long-term culture conditions. AJVR 2007;68(7):709-715.
**Dasuquin® contains FCHG49® Glucosamine Hydrochloride, TRH122® Low Molecular Weight Sodium Chondroitin Sulfate, and NMX1000™ Avocado/Soybean Unsaponifiables, Nutramax Laboratories® exclusive proprietary researched specifications.
U.S. Patent No. 6,797,289
Additional Patent Pending.
***Source: Surveys conducted in October 2001, March 2004 and February 2007 of small animal veterinarians who recommended oral joint health supplements. Surveys conducted in the Fall of 2002 and March 2004 of equine veterinarians who recommended oral joint health supplements.

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